Contrary to minimally invasive surgical thyroid techniques and thermal ablation with radiofrequency, Mod\u00ecLite is the mini-invasive treatment par excellence: thanks to the access with very fine needles (with a caliber less than 1 mm) and 300micron fiber optic Mod\u00ecLite is defined micro-invasive treatment.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″][mk_padding_divider size=”50″][mk_gallery images=”5879,5880,5881,5882″ column=”2″ height=”600″ item_spacing=”0″][mk_fancy_title color=”#252f5a” size=”16″ font_weight=”600″ font_family=”Titillium+Web” font_type=”google”]1.\/2. LA332 Esaote probe with dedicated multi-fibre Guiding System
\n3. Biopsy Software related to multi-fibre Guiding System \/ 4.Planning Software[\/mk_fancy_title][\/vc_column_inner][\/vc_row_inner][mk_padding_divider][\/vc_column][\/mk_page_section][mk_page_section bg_image=”http:\/\/echolaser.pl\/wp-content\/uploads\/2017\/12\/screen-shot-2017-12-12-at-15.02.44.png” bg_color=”#0582c8″ bg_position=”center center” bg_repeat=”no-repeat” bg_stretch=”true” min_height=”0″ padding_top=”20″ padding_bottom=”20″ visibility=”hidden-nb” sidebar=”sidebar-1″][vc_column][mk_padding_divider size=”640″][\/vc_column][\/mk_page_section][mk_page_section bg_image=”http:\/\/echolaser.pl\/wp-content\/uploads\/2017\/12\/s.png” bg_color=”#0582c8″ bg_position=”center center” bg_repeat=”no-repeat” enable_3d=”true” min_height=”0″ padding_top=”20″ padding_bottom=”20″ sidebar=”sidebar-1″][vc_column][mk_padding_divider size=”140″][mk_fancy_title color=”#ffffff” size=”20″ font_weight=”600″ font_family=”Titillium+Web” font_type=”google”]The benefits of ModiLite[\/mk_fancy_title][mk_fancy_title color=”#ffffff” size=”17″ line_height=”180″ font_weight=”500″ font_family=”none”]\n
Surgical removal (thyroidectomy) consists of removal of the entire gland and is in some cases an excessive action which, together with the nodule, also removes healthy glandular tissue that is still able to produce the hormones necessary for the body, forcing life-long hormonal therapy on the patient.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″][mk_fancy_title color=”#252f5a” size=”20″ font_weight=”600″ font_family=”Titillium+Web” font_type=”google”]What is thyroid nodule disease?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515092884166{margin-bottom: 0px !important;}”]The thyroid nodule is one of the most common diseases of the thyroid, the butterfly-shaped endocrine gland located in our throat, which through the two hormones produced \u2013 thyroxine (T-4) and triiodothyronine (T-3) \u2013 regulates numerous physiological functions, including our metabolism. Thyroid problems, quite common in women, are more frequent in areas low in iodine. This is the reason why doctors recommend holidays by the sea at early age if possible, as it is rich in this substance that should not be lacking in our diet. Thyroid nodules \u2013 also called nodular goitre \u2013 can also affect children and young people, but they are more frequent in women aged between 50 and 60.<\/p>\n
The thyroid nodule is a rounded tumefaction that can be either single or multiple, in which case we are talking about multi-nodular goitre, one of the most common diseases of this butterfly-shaped endocrine gland (the thyroid). The nodules may be solid, cystic (containing liquid) or mixed. They are generally small, so in many cases a thyroid nodule is entirely asymptomatic and only discovered by chance, but it can also measure several centimetres and cause compression problems with alterations to the appearance of the neck.<\/p>\n
ModiLite currently offers excellent efficacy in reducing predominantly symptomatic solid or mixed benign nodules.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_tab][vc_tab title=”Clinical cases” tab_id=”1513089091-2-58″][mk_padding_divider size=”80″][vc_row_inner][vc_column_inner width=”1\/2″][mk_fancy_title color=”#252f5a” size=”20″ font_weight=”600″ font_family=”Titillium+Web” font_type=”google”]Clinical Case no.1
\n[\/mk_fancy_title][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]Benign Thyroid Nodule[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515093044069{margin-bottom: 0px !important;}”]A patient with a solid isoechoic nodule (volume 20ml) in the right thyroid lobe, underwent Laser Thermotherapy. During the treatment no discomfort was reported by the patient.[\/vc_column_text][mk_image src=”http:\/\/echolaser.pl\/wp-content\/uploads\/2017\/12\/graziano-ceus-300×227.png” image_size=”full” margin_bottom=”30″][vc_column_text css=”.vc_custom_1515093069938{margin-bottom: 0px !important;}”]CEUS image after the treatment showing the hypoechoic zone of the coagulation area<\/p>\n
The ultrasound scan at the two-year follow-up showed a reduction in the nodule volume equal to 70% compared to the basal volume.[\/vc_column_text][mk_image src=”http:\/\/echolaser.pl\/wp-content\/uploads\/2017\/12\/graziano_prepost-300×116.jpg” image_size=”full” margin_bottom=”30″][vc_column_text css=”.vc_custom_1515093084140{margin-bottom: 0px !important;}”]US images before the treatment and two-year follow-up showing the reduction of the nodule<\/p>\n
Images by courtesy of Dr. Rago (Cisanello Hospital, Pisa)<\/em>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″][mk_fancy_title color=”#252f5a” size=”20″ font_weight=”600″ font_family=”Titillium+Web” font_type=”google”]Clinical Case no.2[\/mk_fancy_title][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]Metastatic Lymph nodes in the neck[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515093119305{margin-bottom: 0px !important;}”]Patient with metastatic lymph node from papillary thyroid carcinoma has been treated with Laser Thermotherapy with two fibres.[\/vc_column_text][mk_image src=”http:\/\/echolaser.pl\/wp-content\/uploads\/2017\/12\/ceus-linfo-pre-300×251.png” image_size=”full” margin_bottom=”30″][vc_column_text css=”.vc_custom_1515093130592{margin-bottom: 0px !important;}”]CEUS image showing the high absorption of the contrast of the pathological lymph node[\/vc_column_text][mk_image src=”http:\/\/echolaser.pl\/wp-content\/uploads\/2017\/12\/eco-linfo-durante-273×300.png” image_size=”full” margin_bottom=”30″][vc_column_text css=”.vc_custom_1515093149794{margin-bottom: 0px !important;}”]US image showing two fibres inside the lymph node[\/vc_column_text][mk_image src=”http:\/\/echolaser.pl\/wp-content\/uploads\/2017\/12\/ceus-linfo-post-300×249.png” image_size=”full” margin_bottom=”30″][vc_column_text css=”.vc_custom_1515093163801{margin-bottom: 0px !important;}”]CEUS image showing the absence of enhancement after the treatment<\/p>\n Images by courtesy of Dr. Giovanni Mauri (IEO Hospital, Milan)<\/em>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_tab][vc_tab title=”FAQ” tab_id=”1513095444481-2-7″][mk_padding_divider size=”80″][mk_fancy_title color=”#252f5a” size=”20″ font_weight=”600″ font_family=”Titillium+Web” font_type=”google”]FAQ – Your frequently asked questions, here you can find answers.[\/mk_fancy_title][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]Why should I consider undergoing Mod\u00ecLite to treat my nodule?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515091612691{margin-bottom: 0px !important;}”]Mod\u00ecLite is indicated in the treatment of solid or mixed benign symptomatic nodules with a repeated cytological diagnosis of benignity.[\/vc_column_text][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]How is the Mod\u00ecLite treatment performed?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515091939103{margin-bottom: 0px !important;}”]One or two optical fibres are inserted via ultrasound guidance into the nodule through extremely fine *Long-term Efficacy of Ultrasound-guided Laser Ablation for Benign Solid Thyroid Nodules. Results of a Three-year Multicenter Prospective Randomized Trial \u2013 JCEM July 2014<\/em>[\/vc_column_text][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]Why should I choose Mod\u00ecLite over other ablative techniques?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515092315910{margin-bottom: 0px !important;}”]Because its effectiveness has been widely demonstrated after a long period of experimentation and in clinical practice its benefits have been evaluated over the years. It is estimated that since being launched, there have been approximately 4.000 patients treated in Italy with a 10-year follow-up.[\/vc_column_text][\/vc_tab][vc_tab title=”Publications” tab_id=”1513096235305-3-5″][mk_padding_divider size=”80″][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]Benign Thyroid Nodule[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515093261222{margin-bottom: 0px !important;}”]A comparison of laser with radiofrequency ablation for the treatment of benign thyroid nodules: a propensity score matching analysis.\u00a0<\/u><\/strong> Percutaneous laser ablation for benign thyroid nodules: a meta-analysis.\u00a0<\/u><\/strong> Laser ablation is more effective for spongiform than solid thyroid nodules. A 4-year retrospective follow-up study.<\/u><\/strong> Benign thyroid nodules treatment using percutaneous laser ablation (PLA) and radiofrequency ablation (RFA)<\/u><\/strong>. Detection of the Single-Session Complete Ablation Rate by Contrast-Enhanced Ultrasound during Ultrasound-Guided Laser Ablation for Benign Thyroid Nodules: A Prospective Study\u00a0<\/u><\/strong> AACE\/AME\/ETA Thyroid Nodule Guidelines\u00a0<\/u><\/strong> Outcomes and Risk Factors for Complications of Laser Ablation for Thyroid Nodules. A Multicenter Study on 1531 Patients.<\/u><\/strong> Ultrasound-guided percutaneous laser ablation (LA) in treating symptomatic solid benign thyroid nodules: Our experience in 45 patients.<\/u><\/strong> Thyroid nodule morphology affects the efficacy of ultrasound-guided interstitial laser ablation: A nested case-control study.\u00a0<\/u><\/strong> Long-term Efficacy of Ultrasound-Guided Laser Ablation for Benign Solid Thyroid Nodules. Results of a Three-Year Multicenter Prospective Randomized Trial.\u00a0<\/u><\/strong> Laser ablation and 131-iodine: a 24-month pilot study of combined treatment for large toxic nodular goiter.<\/u><\/strong> Diagnosis of endocrine disease: thyroid ultrasound (US) and US-assisted procedures: from the shadows into an array of applications.\u00a0<\/u><\/strong> Clinical review: Nonsurgical, image-guided, minimally invasive therapy for thyroid nodules.\u00a0<\/u><\/strong> Image-guided percutaneous ablation therapies for local recurrences of thyroid nodule.<\/u><\/strong> The administration of anesthetic in the thyroid pericapsular region increases the possibility of side effects during percutaneous laser photocoagulation of thyroid nodules.<\/u><\/strong> Ultrasound-Guided Interstitial Laser Ablation for Thyroid Nodules Is Effective Only at High Total Amounts of Energy: Results From a Three-Year Pilot Study.<\/u><\/strong> Percutaneous Laser Ablation of Cold Benign Thyroid Nodules: A 3-Year Follow-Up Study in 122 Patients.\u00a0<\/u><\/strong> Laser and Radiofrequency Ablation procedures.\u00a0<\/u><\/strong> Treatment of Benign Cold Thyroid Nodules: A Randomized Clinical Trial of Percutaneous Laser Ablation Versus Levothyroxine Therapy or Follow-up\u00a0<\/u><\/strong> Thyroid Tissue: US-guided Percutaneous Interstitial Laser Ablation\u2014A Feasibility Study.\u00a0<\/u><\/strong> Percutaneous laser ablation for treatment of locally recurrent papillary thyroid carcinoma <15\u00a0mm\u00a0<\/u><\/strong> Treatment of Metastatic Lymph Nodes in the Neck from Papillary Thyroid Carcinoma with Percutaneous Laser Ablation.<\/u><\/strong> Percutaneous Laser Ablation of Metastatic Lymph Nodes in the Neck from Papillary thyroid carcinoma: preliminary results.<\/u><\/strong> Percutaneous ultrasound-guided laser ablation is effective for treating selected nodal metastases in papillary thyroid cancer.<\/u><\/strong>
\nGauge needles. Mod\u00ecLite is based on EchoLaser system that integrates the most advanced treatment planning technologies with a special multisource laser system. The treatment session lasts from 10 to 20 minutes, which is the time required for the heat inside the nodule to destroy the treated tissue. There are no incisions or stitches and the entire session, including the preparation time, takes just on 30 minutes.[\/vc_column_text][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]Do I have to have an anaesthetic?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515091967956{margin-bottom: 0px !important;}”]Thanks to the extremely find needles Mod\u00ecLite is a procedure that does not require either a general or local anaesthetic. At times patients report slight discomfort when the needles are inserted and a mild sensation of heat during the treatment. If you like, you can still have a local anaesthetic but bear in mind that if you maintain the sensitivity of your neck and cooperate with the physician this will increase the safety and ensure correct performance of the treatment.[\/vc_column_text][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]What are the recovery times?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515092019622{margin-bottom: 0px !important;}”]You can return to your normal activities the very next day after treatment. During the following months you will just need to carry out follow-ups of the thyroid function and ultrasounds to evaluate the reduction of the volume of the nodule.[\/vc_column_text][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]How many sessions will I need?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515092152192{margin-bottom: 0px !important;}”]The effectiveness of Mod\u00ecLite allows for obtaining good results in one single session. If necessary, the treatment can be repeated without compromising any further therapeutic treatment should this be required.[\/vc_column_text][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]What kind of results can I expect?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515092246983{margin-bottom: 0px !important;}”]Mod\u00ecLite gives rise to the disappearance, or in any case the reduction, of the local systems due to the compression exerted by the nodule on the surrounding structures, thus ensuring a substantial recovery of your quality of life. With protruding nodules the normal morphology of your neck will be restored with obvious aesthetic benefits. The reduction process of the nodule, which occurs thanks to the body\u2019s natural cellular repair mechanisms, takes a couple of months.[\/vc_column_text][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]Has Mod\u00ecLite been clinically tested?[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515092281838{margin-bottom: 0px !important;}”]Clinical trials* have demonstrated that after a single treatment, Mod\u00ecLite causes a 50% reduction of the nodular volume in the great majority of patients and that this reduction remains stable over time. Complications have been extremely rare and only of a transient nature.<\/p>\n
\nPacella CM et al
\nInt J Hyperthermia. 2017 Jun 12:1-9.<\/em><\/p>\n
\nSui WF, Li JY, Fu JH.
\nOncotarget. 2017 May 17.<\/em><\/p>\n
\nNegro R, Salemb TM and Greco G.\u00a0<\/em>
\nInt J Hyperthermia. 2016 Nov;32(7):822-8.<\/p>\n
\nMauri G, Cova L, Monaco CG, Sconfienza LM, Corbetta S, Benedini S, Ambrogi F, Milani V, Baroli A, Ierace T& Solbiati L<\/em>
\nInt J Hyperthermia. 2016 Nov 15:1-5.<\/p>\n
\nShuhua Ma, Ping Zhou, XiaominWu, Shuangming Tian, and Yongfeng Zhao\u00a0<\/em>
\nBioMed Research International Volume 2016 (2016), Article ID 9565364, 8 pages<\/p>\n
\nGharib H, Papini E, Garber JR, Duick DS, Harrel RM, Heged\u00fcs L, Paschke R, Valcavi R, Vitti P<\/em>
\nEndocr Pract. 2016;22 (Suppl 1)<\/p>\n
\nPacella CM, Mauri G, Achille G, Barbaro D, Bizzarri G, De Feo P, Di Stasio E, Esposito R, Gambelunghe G, Misischi I, Raggiunti B, Rago T, Patelli GL, D\u2019Este S, Vitti P, Papini E.<\/em>
\nJ Clin Endocrinol Metab. 2015 Oct;100(10):3903-10.<\/p>\n
\nAchille G, Zizzi S, Di Stasio E, Grammatica A, Grammatica L.<\/em>
\nHead Neck. 2014 Dec 18.<\/p>\n
\nGambelunghe G, Bini V, Stefanetti E, Colella R, Monacelli M, Avenia N, De Feo P.\u00a0<\/em>
\nInt J Hyperthermia. 2014 Oct 7:1-4<\/p>\n
\nPapini E, Rago T, Gambelunghe G, Valcavi R, Bizzarri G, Vitti P, De Feo P, Riganti F, Misischi I, Di Stasio E, Pacella CM.\u00a0<\/em>
\nJ Clin Endocrinol Metab. 2014 Oct;99(10)<\/p>\n
\nChianelli M, Bizzarri G, Todino V, Misischi I, Bianchini A, Graziano F, Guglielmi R, Pacella CM, Gharib H, Papini E.\u00a0<\/em>
\nJ Clin Endocrinol Metab. 2014 Jul;99(7)<\/p>\n
\nPapini E, Pacella CM, Hegedus L.\u00a0<\/em>
\nEur J Endocrinol. 2014 Mar 14;170(4):R133-46<\/p>\n
\nGharib H, Heged\u00fcs L, Pacella CM, Baek JH, Papini E\u00a0<\/em>
\nJ Clin Endocrinol Metab. 2013 Oct;98(10):3949-57.<\/p>\n
\nPacella CM and Papini E\u00a0<\/em>
\nJ.Endocrinol.Invest.36: 61-70;2013<\/p>\n
\nGambelunghe G, Bini V, Monacelli M, Avenia N, D\u2019Ajello M, Colella R, De Feo P\u00a0<\/em>
\nLasers Surg Med. 2013<\/p>\n
\nGambelunghe G, Fede R, Bini V, Monacelli M, Avenia N, D\u2019Ajello M, Colella R, Nasini G, De Feo P<\/em>
\nSurg Innov. 2012<\/p>\n
\nValcavi R,Riganti F,Bertani A,Formisano D, Pacella CM<\/em>
\nThyroid 2010; Volume 20, Number 11<\/p>\n
\nValcavi R, Bertani A, Pesenti , Al Jandali, Frasoldati, Formisano, Pacella CM.<\/em>
\nThyroid Ultrasound and Ultrasound-Guided FNA
\nSpringer<\/p>\n
\nPapini E, Guglielmi R, Bizzarri G, Graziano F, Bianchini A, Brufani C, Pacella S, Valle D, Pacella CM.<\/em>
\nThyroid. 2007 Mar;17(3):229-35.<\/p>\n
\nPacella CM, Bizzarri G, Guglielmi R, Anelli V, Bianchini A, Crescenzi A, Pacella S, Papini E.<\/em>
\nRadiology. 2000 Dec;217(3):673-7[\/vc_column_text][mk_fancy_title color=”#0083c5″ size=”17″ line_height=”140″ font_weight=”500″ font_family=”none”]Metastatic Lymph Node in the neck[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515093331985{margin-bottom: 0px !important;}”]Role of ultrasound in the assessment of percutaneous laser ablation of cervical metastatic lymph nodes from thyroid carcinoma.<\/u><\/strong>
\nZhang L, Zhou W, Zhan W.<\/em>
\nActa Radiol. 2017 Jan 1:284185117721261.<\/p>\n
\nZhou W, Zhang L, Zhan W, Jiang S, Zhu Y, Xu S.<\/em>
\nClin Radiol 2016 Dec;71(12):1233-1239.<\/p>\n
\nMauri G, Cova L, Ierace T, Baroli A, Di Mauro E, Pacella CM, Goldberg SN, Solbiati L\u00a0<\/em>
\nCardiovasc Intervent Radiol. 2016 Jul;39(7):1023-30<\/p>\n
\nMauri G, Cova L, Tondolo T, Ierace T, Baroli A, Di Mauro E, Pacella CM, Goldberg SN, Solbiati L\u00a0<\/em>
\nJ Clin Endocrinol Metab. 2013 May 10.<\/p>\n
\nPapini E, Bizzarri G, Bianchini A, Valle D, Misischi I, Guglielmi R, Salvatori M, Solbiati L, Crescenzi A, Pacella CM, Gharib H.<\/em>
\nJ Clin Endocrin Metab, 2013 Jan;98(1):E92-7[\/vc_column_text][\/vc_tab][vc_tab title=”Clinical Trials” tab_id=”1513096936469-4-1″][mk_padding_divider size=”80″][mk_fancy_title color=”#252f5a” size=”20″ font_weight=”600″ font_family=”Titillium+Web” font_type=”google”]Multicentric Randomized Controlled Study of Percutaneous Laser Ablation Versus Follow Up in Benign Thyroid Nodules. Long Term Results[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515093459021{margin-bottom: 0px !important;}”]Multicentre Randomized Clinical Trial
\nNo. of patients enrolled: 200
\nReference Study Centres: 4, Azienda Ospedaliero-Universitaria di Pisa \u2013 Presidio di Cisanello, Ospedale Regina Apostolorum, Azienda Ospedaliera di Perugia, Arcispedale Santa Maria Nuova
\nStudy status: Completed
\nRegistered on ClinicalTrial.gov:\u00a0https:\/\/clinicaltrials.gov\/ct2\/show\/NCT00858104<\/a>
\nPublications of the results:\u00a0Long-term Efficacy of Ultrasound-Guided Laser Ablation for Benign Solid Thyroid Nodules. Results of a Three-Year Multicenter Prospective Randomized Trial,\u00a0<\/a>Papini E, Rago T, Gambelunghe G, Valcavi R, Bizzarri G, Vitti P, De Feo P, Riganti F, Misischi I, Di Stasio E, Pacella CM. J Clin Endocrinol Metab. 2014 Oct[\/vc_column_text][mk_fancy_title color=”#252f5a” size=”20″ font_weight=”600″ font_family=”Titillium+Web” font_type=”google”]Laser Ablation Versus Radiofrequency Ablation for Thyroid Nodules (LARA)[\/mk_fancy_title][vc_column_text css=”.vc_custom_1515093485261{margin-bottom: 0px !important;}”]\n